ethyl N,N-dimethyl-beta-alaninate
3-Dimethylaminoacrylic acid ethyl ester
CAS: 924-99-2;1117-37-9
Molecular Formula: C7H13NO2
ethyl N,N-dimethyl-beta-alaninate - Names and Identifiers
ethyl N,N-dimethyl-beta-alaninate - Physico-chemical Properties
| Molecular Formula | C7H13NO2 |
| Molar Mass | 143.18 |
| Density | 1 |
| Melting Point | 17-18 °C |
| Boling Point | 118-121 °C (7.501 mmHg) |
| Flash Point | 105 °C |
| Water Solubility | 90 g/L (25 ºC) |
| Vapor Presure | 0.683mmHg at 25°C |
| Appearance | Colorless to yellow liquid |
| Specific Gravity | 0.996 |
| Color | Clear yellow to light orange |
| pKa | 6.67±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.5105-1.5125 |
| MDL | MFCD00144269 |
ethyl N,N-dimethyl-beta-alaninate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R43 - May cause sensitization by skin contact R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37 - Wear suitable gloves. S24 - Avoid contact with skin. S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29299090 |
ethyl N,N-dimethyl-beta-alaninate - Reference Information
| Application | ethyl 3-(N,N-dimethylamino) acrylate is a widely used quaternary amine acrylate, with the characteristics of esters, olefins, amines, can be used for the preparation of fungicides (fluorozolamide, biphenylamine, pyrazolineamine, etc.) 3-difluoromethyl -1-methyl pyrazole-4-carboxylic acid, can also be used for the synthesis of anti-infective quinolones (ciprofloxacin, moxifloxacin, levofloxacin, norfloxacin, etc.). In recent years, the industry has also taken N,N-dimethylaminoethyl acrylate as the main raw material of special chemicals such as fiber treatment agent, coating, ion exchange resin, paper strength enhancer, dyeing modifier, etc. |
| preparation | first ethyl acetate (880kg,10kmol) and aqueous dimethylamine solution (40% kg,11kmol) with a concentration of 1237.5 3000L stainless steel reaction kettle was pumped in sequence, and the motor was turned on for stirring. After stirring evenly, formic acid (690kg,15kmol) was pumped. After feeding, steam is introduced into the reactor jacket, and the temperature in the reactor is heated to 125 ℃, at which the pressure of the reaction system is about 0.2MPa, and then nitrogen is introduced into the reactor to pressurize to 0.55MPa, then, the heat preservation and closed reaction was started for 16H. When the pressure decreases during the holding period, nitrogen is introduced to maintain the pressure at 0.55MPa. After the completion of the heat preservation, the circulating water was introduced into the reactor jacket, and the temperature in the reactor was cooled to below 45 °c. After completion of the temperature reduction, the resulting solution was transferred to a freeze dryer, and the water content in the product was made to be less than 0.5% by a freeze-drying process, thereby obtaining a crude ethyl 3-(N,N-dimethylamino) acrylate product. After Freeze-drying, The crude ethyl N,N-dimethylaminoacrylate was transferred to a rectification kettle and subjected to vacuum distillation at a vacuum of 0.095MPa and a temperature of 150 ℃ to obtain 1314.2kg of colorless and transparent 3-(N, ethyl N-dimethylamino) acrylate was the final product in a molar yield of 91.9% and a gas chromatographic purity of 99.52%. |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Multiple SpecificationsSpot supply
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Multiple Specifications
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: Gatifloxacin Impurity 49 Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Ethyl 3-(N,N-Dimethylamino)Acrylate Visit Supplier Webpage Request for quotationCAS: 1117-37-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Multiple SpecificationsSpot supply
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Multiple Specifications
Product Name: 3-Dimethylaminoacrylic acid ethyl ester Request for quotationCAS: 924-99-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: Gatifloxacin Impurity 49 Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Ethyl 3-(N,N-Dimethylamino)Acrylate Visit Supplier Webpage Request for quotationCAS: 1117-37-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History